Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 17/20 | 0.55 |
| ▸ | CNR2 | P34972 | 9/20 | 0.55 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889175 | 0.87 | CNR1 (0.54) | CNR1CNR2 | |
| SCHEMBL643913 | 0.87 | CNR1 (0.64) | CNR1CNR2MARS1 | |
| SCHEMBL643914 | 0.87 | CNR1 (0.64) | CNR1CNR2MARS1 | |
| SCHEMBL3889702 | 0.86 | CNR1 (0.55) | CNR1CNR2 | |
| SCHEMBL13867068 | 0.85 | CNR1 (0.78) | CNR1CNR2 | |
| SCHEMBL13867071 | 0.85 | CNR1 (0.78) | CNR1CNR2 | |
| SCHEMBL4702795 | 0.85 | CNR1 (0.69) | CNR1CNR2MARS1 | |
| SCHEMBL177054 | 0.85 | CNR1 (0.72) | CNR1CNR2MARS1 | |
| SCHEMBL5416714 | 0.85 | CNR1 (0.69) | CNR1CNR2MARS1 | |
| SCHEMBL257390 | 0.85 | CNR1 (0.72) | CNR1CNR2MARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7524964-B2 | Tetrahydrothiopyrano pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-28 | — | — | US | claimed |
| EP-1863479-B1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS CROSS REFERENCE TO RELATED APPLICATIONS | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-10 | — | — | EP | claimed |
| US-20080085899-A1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS | LIOTTA FINA | 2008-04-10 | — | — | US | claimed |
| EP-1863479-A1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS CROSS REFERENCE TO RELATED APPLICATIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-12-12 | — | — | EP | claimed |
| WO-2006107561-A1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-10-12 | — | — | WO | claimed |
| US-20060223798-A1 | Tetrahydrothiopyrano pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2006-10-05 | — | — | US | claimed |
| US-7524964-B2 | Tetrahydrothiopyrano pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2009-04-28 | — | — | US | disclosed |
| EP-1863479-B1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS CROSS REFERENCE TO RELATED APPLICATIONS | JANSSEN PHARMACEUTICA NV (BE) | 2008-12-10 | — | — | EP | disclosed |
| US-20080085899-A1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS | LIOTTA FINA | 2008-04-10 | — | — | US | disclosed |
| US-20060223798-A1 | Tetrahydrothiopyrano pyrazole cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223798-A1 | Tetrahydrothiopyrano pyrazole cannabinoid modulators | CNR1, CNR2, GPR18 | CNR1 1/4885CNR2 2/4885MARS1 4645/4885 |
| US-20080085899-A1 | TETRAHYDROTHIOPYRANO PYRAZOLE CANNABINOID MODULATORS | CNR1, CNR2, GPR18 | CNR1 1/4885CNR2 2/4885MARS1 4645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.