SCHEMBL3888967

SCHEMBL3888967

Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)NC[C@H]1CCCN(c2ccccc2CC(=O)O)C1

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 14/20 0.68
CHRM4 P08173 3/20 0.55
PPARD Q03181 4/20 0.51
PPARG P37231 1/20 0.51
GAA P10253 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45
NPC1 O15118 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3892378 1.00 PPARA (0.68) PPARACHRM4PPARDPPARGGAA
SCHEMBL3888972 1.00 PPARA (0.68) PPARACHRM4PPARDPPARGGAA
SCHEMBL5487834 0.94 PPARA (0.60) PPARACHRM4PPARDPPARGGAA
SCHEMBL3892372 0.92 PPARA (0.65) PPARACHRM4PPARDPPARGGAA
SCHEMBL2069036 0.89 PPARA (0.73) PPARACHRM4PPARDPPARGGAA
SCHEMBL2070819 0.89 PPARA (0.73) PPARACHRM4PPARDPPARGGAA
SCHEMBL2069034 0.89 PPARA (0.73) PPARACHRM4PPARDPPARGGAA
SCHEMBL3890236 0.88 PPARA (0.63) PPARACHRM4PPARDPPARGGAA
SCHEMBL3905841 0.87 PPARA (0.57) PPARACHRM4PPARDPPARGGAA
SCHEMBL3889709 0.87 PPARA (0.68) PPARACHRM4PPARDPPARGGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090036489-A1 Novel Cyclic Aminophenylalkanoic Acid Derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2009-02-05 US claimed
EP-1862464-A1 NOVEL CYCLIC AMINOPHENYLALKANOIC ACID DERIVATIVE Kyorin Pharmaceutical Co., Ltd. (JP) 2007-12-05 EP claimed
US-20090036489-A1 Novel Cyclic Aminophenylalkanoic Acid Derivative KYORIN PHARMACEUTICAL CO., LTD. (JP) 2009-02-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036489-A1 Novel Cyclic Aminophenylalkanoic Acid Derivative PPARA, PPARD, PPARG PPARA 1/4885CHRM4 2809/4885PPARD 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.