Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892378 | 0.94 | PPARA (0.68) | PPARAHPGDNPC1PPARDSMN1; SMN2 | |
| SCHEMBL3888972 | 0.94 | PPARA (0.68) | PPARAHPGDNPC1PPARDSMN1; SMN2 | |
| SCHEMBL3888967 | 0.94 | PPARA (0.68) | PPARAHPGDNPC1PPARDSMN1; SMN2 | |
| SCHEMBL3905841 | 0.93 | PPARA (0.57) | PPARAHPGDNPC1PPARDSMN1; SMN2 | |
| SCHEMBL3892372 | 0.86 | PPARA (0.65) | PPARAPPARDSMN1; SMN2CHRM4GAA | |
| SCHEMBL3896907 | 0.85 | CHRM4 (0.53) | PPARANPC1PPARDCHRM4ALDH1A1 | |
| SCHEMBL2069036 | 0.83 | PPARA (0.73) | PPARANPC1PPARDSMN1; SMN2CHRM4 | |
| SCHEMBL2069034 | 0.83 | PPARA (0.73) | PPARANPC1PPARDSMN1; SMN2CHRM4 | |
| SCHEMBL2070819 | 0.83 | PPARA (0.73) | PPARANPC1PPARDSMN1; SMN2CHRM4 | |
| SCHEMBL3890236 | 0.82 | PPARA (0.63) | PPARAPPARDSMN1; SMN2CHRM4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1862464-A1 | NOVEL CYCLIC AMINOPHENYLALKANOIC ACID DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2007-12-05 | — | — | EP | disclosed |