Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3889127 | 1.00 | KMT2A (0.45) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3889681 | 0.89 | KMT2A (0.52) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3889675 | 0.89 | KMT2A (0.52) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3887256 | 0.87 | KMT2A (0.53) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3887258 | 0.87 | KMT2A (0.53) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3885818 | 0.80 | KMT2A (0.41) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3885822 | 0.80 | KMT2A (0.41) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3891294 | 0.79 | SIRT5 (0.43) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3891296 | 0.79 | SIRT5 (0.43) | KMT2AMEN1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL3897763 | 0.79 | KMT2A (0.43) | KMT2AMEN1L3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534273-B2 | Cationic pyrazolone dyes, method for production thereof and coloring agents for keratin fibers containing said compounds | WELLA AG (DE) | 2009-05-19 | — | — | US | claimed |
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-30 | — | — | US | claimed |
| EP-1771517-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | claimed |
| WO-2006012934-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-02-09 | — | — | WO | claimed |
| US-7534273-B2 | Cationic pyrazolone dyes, method for production thereof and coloring agents for keratin fibers containing said compounds | WELLA AG (DE) | 2009-05-19 | — | — | US | disclosed |
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-30 | — | — | US | disclosed |
| EP-1773929-A1 | STABILISER COMPOSITION MADE FROM LIQUID AND SOLID UV-ABSORBERS | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-18 | — | — | EP | disclosed |
| EP-1771517-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006012934-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-02-09 | — | — | WO | disclosed |
| WO-2006013071-A1 | STABILISER COMPOSITION MADE FROM LIQUID AND SOLID UV-ABSORBERS | BASF AKTIENGESELLSCHAFT (DE) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | KRT18, KLK5, IK | KMT2A 3682/4885MEN1 4265/4885L3MBTL1 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.