Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5095344 | 0.86 | TP53 (0.50) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL29944162 | 0.84 | CYP3A4 (0.65) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL132541 | 0.84 | CYP3A4 (0.65) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL232779 | 0.84 | TP53 (0.64) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL28837769 | 0.82 | CYP3A4 (0.63) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL28837773 | 0.82 | CYP3A4 (0.63) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| Methane SCHEMBL7896214 | 0.82 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL2299193 | 0.82 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL3088495 | 0.82 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL9133420 | 0.82 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180164240-A1 | SENSOR FOR DETECTION OF ANALYTES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-06-14 | — | — | US | disclosed |
| US-7507585-B2 | Methods and systems for indentifying and monitoring S-nitrosothiols in biological samples | WHALEN ERIN J | 2009-03-24 | — | — | US | disclosed |
| US-7150875-B2 | Recombinant Plasmodium vivax merozoite protein-1 p42 vaccine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2006-12-19 | — | — | US | disclosed |
| US-20060264619-A1 | Plasmodium falciparum AMA-1 protein and uses thereof | LANAR DAVID E | 2006-11-23 | — | — | US | disclosed |
| WO-2006076225-A2 | METHODS AND SYSTEMS FOR IDENTIFYING AND MONITORING S-NITROSOTHIOLS IN BIOLOGICAL SAMPLES | WHALEN ERIN J (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060154376-A1 | Methods and systems for indentifying and monitoring S-nitrosothiols in biological samples | WHALEN ERIN J | 2006-07-13 | — | — | US | disclosed |
| US-7060276-B2 | Plasmodium falciparum AMA-1 protein and uses thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2006-06-13 | — | — | US | disclosed |
| US-7029685-B2 | Plasmodium falciparum AMA-1 protein and uses thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2006-04-18 | — | — | US | disclosed |
| US-20030157650-A1 | Recombinant P. vivax merozoite protein-1 p42 vaccine | ARMY, UNITED STATES OF AMERICA, THE, AS REPRESENTED BY THE SECRETARY | 2003-08-21 | — | — | US | disclosed |
| US-20030138450-A1 | Plasmodium falciparum AMA-1 protein and uses thereof | ARMY, UNITED STATES | 2003-07-24 | — | — | US | disclosed |
| US-20030032787-A1 | Plasmodium falciparum AMA-1 protein and uses thereof | UNITED STATES ARMY | 2003-02-13 | — | — | US | disclosed |
| WO-2002077195-A9 | PLASMODIUM FALCIPARUM AMA-1 PROTEIN AND USES THEREOF | US ARMY (US) | 2003-01-09 | — | — | WO | disclosed |