Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.48 |
| ▸ | CASR known ✓ | P41180 | 1/20 | 0.47 |
| ▸ | CYP19A1 known ✓ | P11511 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2299193 | 1.00 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| SCHEMBL232779 | 0.98 | TP53 (0.64) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| SCHEMBL28138389 | 0.95 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| SCHEMBL9133420 | 0.95 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| Hydrochloric Acid SCHEMBL1905625 | 0.95 | CYP3A4 (0.63) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| SCHEMBL28117879 | 0.95 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| SCHEMBL28172063 | 0.95 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| Methane SCHEMBL7896214 | 0.95 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| SCHEMBL8060267 | 0.95 | TP53 (0.62) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 | |
| SCHEMBL11650511 | 0.93 | TP53 (0.60) | TP53TDP1CYP3A4SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118685993-B | Antibacterial breathable fabric and preparation process thereof | 广东健业纺织集团有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-112713361-A | Composite lithium-sulfur battery diaphragm and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-04-27 | — | — | CN | claimed |
| CN-221965301-U | Device and system for continuously producing 5-nitro dimethyl isophthalic acid by micro-channel | 成都艾必克医药科技有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-118002050-A | Method, device and system for continuously producing 5-nitro dimethyl isophthalic acid by micro-channel | 成都艾必克医药科技有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-110511593-B | Azo pigment, color filter, colorant and coloring composition for the same, and display device and image pickup element comprising the same | 东洋油墨SC控股株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-109423064-B | Azo pigment, colorant for color filter, coloring composition for color filter, and color filter | 东洋油墨SC控股株式会社 | 2022-05-13 | — | — | CN | disclosed |
| EP-1592738-B1 | RESIN COMPOSITIONS | CIBA HOLDING INC (CH) | 2020-07-29 | — | — | EP | disclosed |
| CN-110511593-A | Azo pigments, colored filter and colorant and coloured composition and display device and photographing element comprising it for it | TOYO INK SC HOLDINGS CO LTD | 2019-11-29 | — | — | CN | disclosed |
| US-7790793-B2 | Amide nucleating agent compositions | CIBA SPECIALTY CHEM. CORP. (US) | 2010-09-07 | — | — | US | disclosed |
| WO-2010069854-A2 | MODIFIED POLYOLEFIN WAXES | BASF SE (DE) | 2010-06-24 | — | — | WO | disclosed |
| US-20070149663-A1 | Resin compositions | CIBA SPECIALTY CHEMICALS CORP. | 2007-06-28 | — | — | US | disclosed |
| EP-1592738-A2 | RESIN COMPOSITIONS | Ciba SC Holding AG (CH) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004072168-A2 | RESIN COMPOSITIONS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-08-26 | — | — | WO | disclosed |
| US-6248306-B1 | MEDICAL DIAGNOSIS | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-06-19 | — | — | US | disclosed |
| US-5128429-A | Low temperature block polymerization without randomization | RAYCHEM LIMITED (GB) | 1992-07-07 | — | — | US | disclosed |
| EP-0154506-B1 | PREPARATION OF ORGANIC POLYMERS | RAYCHEM LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| US-4999411-A | Polythioethers, polythiocarbonates, polythioamides, polythioimides | RAYCHEM LIMITED (GB) | 1991-03-12 | — | — | US | disclosed |
| US-4960835-A | ENGINEERING THERMOPLASTICS | RAYCHEM LIMITED (GB) | 1990-10-02 | — | — | US | disclosed |
| US-4845179-A | CONDENSATION POLYMERIZATION | RAYCHEM LIMITED (GB) | 1989-07-04 | — | — | US | disclosed |
| EP-0154506-A2 | Preparation of organic polymers | RAYCHEM LIMITED (GB) | 1985-09-11 | — | — | EP | disclosed |