⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL327516 | 0.78 | ALDH1A1 (0.35) | — | |
| SCHEMBL7044812 | 0.76 | ALDH1A1 (0.41) | — | |
| SCHEMBL173228 | 0.76 | ALDH1A1 (0.52) | — | |
| SCHEMBL11616346 | 0.76 | ALDH1A1 (0.52) | — | |
| SCHEMBL1897643 | 0.76 | — | — | |
| SCHEMBL11695456 | 0.75 | — | — | |
| SCHEMBL676588 | 0.74 | — | — | |
| SCHEMBL10715503 | 0.74 | ALDH1A1 (0.39) | — | |
| SCHEMBL207433 | 0.74 | — | — | |
| SCHEMBL170266 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435962-A4 | TREATMENT OF TYPE I DIABETES | CELL PATHWAYS INC (US) | 2009-04-15 | — | — | EP | disclosed |
| US-20060252762-A1 | Methods for treatment of multiple sclerosis | WHITEHEAD CLARK M | 2006-11-09 | — | — | US | disclosed |
| US-20060100210-A1 | Methods for treatment of scleroderma | WHITEHEAD CLARK M | 2006-05-11 | — | — | US | disclosed |
| US-6906064-B2 | Method for treating a patient with neoplasia using Iressa | OSI PHARMACEUTICALS, INC. | 2005-06-14 | — | — | US | disclosed |
| EP-1435961-A4 | TREATMENT FOR LUPUS ERYTHEMATOSUS | CELL PATHWAYS INC (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1435940-A4 | TREATMENT OF SCLERODERMA | CELL PATHWAYS INC (US) | 2005-04-20 | — | — | EP | disclosed |
| EP-1435962-A2 | TREATMENT OF TYPE I DIABETES | Cell Pathways, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1435782-A1 | TREATMENT FOR CYSTIC FIBROSIS | Cell Pathways, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1435961-A2 | TREATMENT FOR LUPUS ERYTHEMATOSUS | Cell Pathways, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1435940-A1 | TREATMENT OF SCLERODERMA | Cell Pathways, Inc. (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1044187-A1 | N-BENZYL-3-INDENYLACETAMIDES DERIVATIVES FOR TREATING NEOPLASIA | OSI Pharmaceuticals, Inc. (US) | 2000-10-18 | — | — | EP | disclosed |
| US-6066634-A | PHOSPHODIESTERASE INHIBITOR | CELL PATHWAYS, INC. (US) | 2000-05-23 | — | — | US | disclosed |
| US-5948779-A | APOPTOSIS; ANTICANCER AGENT | CELL PATHWAYS, INC. (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1999031065-A1 | N-BENZYL-3-INDENYLACETAMIDES DERIVATIVES FOR TREATING NEOPLASIA | CELL PATHWAYS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |
| EP-0278674-B1 | STERILIZATION OF COMPOSITIONS OF LIMITED STABILITY | COOK IMAGING CORPORATION (US) | 1992-08-12 | — | — | EP | disclosed |
| US-4863714-A | CARBOXYLATE BUFFER, ACIDITY, HEAT TREATMENT | COOK IMAGING CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |
| EP-0278674-A2 | Sterilization of compositions of limited stability | COOK IMAGING CORPORATION (US) | 1988-08-17 | — | — | EP | disclosed |
| EP-0116254-B1 | NEW PHENYLTHIONOPHOSPHONIC ACID ESTERS | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1986-10-15 | — | — | EP | disclosed |
| EP-0116254-A1 | New phenylthionophosphonic acid esters | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1984-08-22 | — | — | EP | disclosed |
| US-4443439-A | Pesticidal phenylthionophosphonic acid esters | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |