Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145759 | 0.79 | DHODH (0.43) | DHODHLMNARAB9ASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10739654 | 0.78 | DHODH (0.42) | DHODHLMNAEPHX2RAB9ASMN1; SMN2 | |
| SCHEMBL3059989 | 0.78 | DHODH (0.42) | DHODHLMNAEPHX2CYP2C19 | |
| SCHEMBL8808173 | 0.78 | DHODH (0.42) | DHODHLMNAALDH1A1KMT2A | |
| SCHEMBL8810575 | 0.76 | DHODH (0.51) | DHODHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8808868 | 0.76 | DHODH (0.51) | DHODHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8810971 | 0.73 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2TP53KMT2A | |
| SCHEMBL8813080 | 0.72 | MAPT (0.49) | DHODHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8809721 | 0.71 | DHODH (0.48) | DHODHLMNARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8811102 | 0.71 | DHODH (0.46) | DHODHLMNARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010507-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | ScheBo Biotech Aktiengesellschaft (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007110068-A2 | NOVEL ISOOXAZOLE DERIVATIVES AND THEIR USES | SCHEBO BIOTECH AG (DE) | 2007-10-04 | — | — | WO | disclosed |