Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL2037264 | 0.93 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL819698 | 0.93 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL1022750 | 0.93 | LMNA (0.47) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL4253510 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL4257037 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL29498110 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL4254722 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL4249773 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL4268429 | 0.89 | LMNA (0.44) | LMNAALDH1A1TSHRFGFR4CA1 | |
| Acrylic Acid SCHEMBL29516833 | 0.89 | LMNA (0.50) | LMNAALDH1A1TSHRFGFR4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598022-B2 | Positive and negative dual function magnetic resist lithography | NATIONAL TAIWAN UNIVERSITY (TW) | 2009-10-06 | — | — | US | disclosed |
| US-20080020325-A1 | Positive and negative dual function magnetic resist lithography | NATIONAL TAIWAN UNIVERSITY (TW) | 2008-01-24 | — | — | US | disclosed |