Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.76 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922176 | 0.90 | KMT2A (0.81) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL642700 | 0.90 | KMT2A (0.81) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| Phosphine SCHEMBL28320532 | 0.88 | KMT2A (0.78) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| Sulfanitran SCHEMBL93837 | 0.86 | KMT2A (1.00) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| Acedapsone SCHEMBL152710 | 0.86 | PKM (0.85) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL11768817 | 0.84 | KMT2A (0.73) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| Acedapsone SCHEMBL28716352 | 0.84 | PKM (0.82) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| Acedapsone SCHEMBL22518385 | 0.84 | PKM (0.82) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| 1,2-Dichloroethane SCHEMBL29197936 | 0.82 | KMT2A (0.69) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL6815786 | 0.82 | MAPT (0.76) | KMT2AMEN1ALDH1A1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531694-B2 | Process for synthesis of 4-4′-diamino-diphenyl-sulfone | LUNDBECK PHARMACEUTICALS ITALY, S.P.A. (IT) | 2009-05-12 | — | — | US | disclosed |
| US-4030994-A | FLUOROXY PENTAFLUOROSULFUR | MERCK & CO., INC. (US) | 1977-06-21 | — | — | US | disclosed |