Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29165629 | 0.91 | TSHR (0.43) | TSHRTDP1ALDH1A1 | |
| Propane SCHEMBL22163895 | 0.87 | TSHR (0.45) | TSHRTDP1ALDH1A1 | |
| SCHEMBL22437 | 0.85 | TSHR (0.56) | TSHRTDP1ALDH1A1 | |
| SCHEMBL13214042 | 0.82 | — | — | |
| SCHEMBL28291040 | 0.81 | TSHR (0.53) | TSHRTDP1ALDH1A1 | |
| SCHEMBL43867 | 0.81 | TSHR (0.53) | TSHRTDP1ALDH1A1 | |
| Propane SCHEMBL325596 | 0.81 | TSHR (0.53) | TSHRTDP1ALDH1A1 | |
| SCHEMBL29280589 | 0.79 | TSHR (0.50) | TSHRTDP1ALDH1A1 | |
| Ethylene SCHEMBL28050612 | 0.79 | TSHR (0.50) | TSHRTDP1ALDH1A1 | |
| Methyl Alcohol SCHEMBL8027284 | 0.79 | TSHR (0.50) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7595338-B2 | Process for preparing 3,3-disubstituted oxindoles and thio-oxindoles | WYETH (US) | 2009-09-29 | — | — | US | disclosed |
| EP-1877377-A2 | PROCESS FOR PREPARING 3,3-DISUBSTITUTED OXINDOLES AND THIO-OXINDOLES | Wyeth (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006118955-A2 | PROCESS FOR PREPARING 3,3-DISUBSTITUTED OXINDOLES AND THIO-OXINDOLES | WYETH (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060247441-A1 | Process for preparing 3,3-disubstituted oxindoles and thio-oxindoles | WYETH (US) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247441-A1 | Process for preparing 3,3-disubstituted oxindoles and thio-oxindoles | TPMT, TH, HTR3C | TSHR 1155/4885TDP1 1370/4885ALDH1A1 1493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.