Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetone SCHEMBL2672348 | 0.85 | PAOX (0.61) | PAOXCA1HDAC3HDAC1HDAC2 | |
| Acetone SCHEMBL4367700 | 0.82 | PAOX (0.58) | PAOXCA1ADH1BADH1AADH7 | |
| Acetic Acid SCHEMBL6367218 | 0.82 | PAOX (0.58) | PAOXCA1FFAR3HDAC3HDAC1 | |
| Acetic Acid SCHEMBL7063721 | 0.80 | ALDH1A1 (0.59) | PAOXADH1BADH1AADH7CES1 | |
| Acetic Acid SCHEMBL7561331 | 0.80 | PAOX (0.56) | PAOXCA1FFAR3HDAC3HDAC1 | |
| Bicarbonate SCHEMBL28444878 | 0.79 | PAOX (0.54) | PAOXCA1FFAR3HDAC3HDAC1 | |
| Acetic Acid SCHEMBL21412814 | 0.79 | TSHR (0.50) | PAOXCA1ADH1BADH1AADH7 | |
| Acetic Acid SCHEMBL5503587 | 0.78 | CA1 (0.61) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Acetic Acid SCHEMBL5265226 | 0.78 | CA1 (0.61) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Diethanolamine SCHEMBL7559033 | 0.78 | CA1 (0.44) | PAOXCA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0866486-B1 | Method of production of electron source substrate provided with electron emitting elements and method of production of image forming apparatus using the substrate | CANON KK (JP) | 2009-01-14 | — | — | EP | disclosed |
| US-7442405-B2 | Method for production of electron source substrate provided with electron emitting element and method for production of electronic device using the substrate | CANON KABUSHIKI KAISHA (JP) | 2008-10-28 | — | — | US | disclosed |
| US-20040213897-A1 | Method for production of electron source substrate provided with electron emitting element and method for production of electronic device using the substrate | CANON KABUSHIKI KAISHA (JP) | 2004-10-28 | — | — | US | disclosed |
| US-20030026893-A1 | Method for production of electron source substrate provided with electron emitting element and method for production of electronic device using the substrate | MIYAMOTO MASAHIKO (JP) | 2003-02-06 | — | — | US | disclosed |
| US-6514559-B1 | High efficiency with less shape irregularity | CANON KABUSHIKI KAISHA (JP) | 2003-02-04 | — | — | US | disclosed |
| EP-0736890-B1 | Metal-containing compostition for forming electron-emitting device and methods of manufacturing electron-emitting device, electron source and image-forming apparatus | CANON KK (JP) | 2002-07-31 | — | — | EP | disclosed |
| EP-1124247-A1 | Metal-containing composition for forming electron-emitting device and methods of manufacturing electron-emitting device,electron source and image-forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-6270389-B1 | Method for forming an electron-emitting device using a metal-containing composition | CANON KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6123876-A | COMPOUND CONTAINING AN ORGANIC ACID GROUP, A TRANSITION METAL AND AN ALCOHOL AMINE, AND WATER. | CANON KABUSHIKI KAISHA (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0866486-A2 | Method for production of electron source substrate provided with electron emitting element and method for production of electronic device using the substrate | CANON KABUSHIKI KAISHA (JP) | 1998-09-23 | — | — | EP | disclosed |
| EP-0736890-A1 | Metal-containing compostition for forming electron-emitting device and methods of manufacturing electron-emitting device, electron source and image-forming apparatus | CANON KABUSHIKI KAISHA (JP) | 1996-10-09 | — | — | EP | disclosed |