Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.64 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208869 | 0.99 | ALDH1A1 (0.62) | ALDH1A1CNR1CNR2 | |
| Ethylene Glycol SCHEMBL26618260 | 0.97 | ALDH1A1 (0.61) | ALDH1A1CNR1CNR2 | |
| SCHEMBL7202735 | 0.94 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2 | |
| SCHEMBL16086048 | 0.94 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2 | |
| SCHEMBL28992552 | 0.94 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2 | |
| SCHEMBL7591414 | 0.94 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2 | |
| SCHEMBL1735177 | 0.94 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2 | |
| SCHEMBL28992543 | 0.94 | ALDH1A1 (0.55) | ALDH1A1CNR1CNR2 | |
| Ethylene Glycol SCHEMBL26618285 | 0.93 | ALDH1A1 (0.54) | ALDH1A1CNR1CNR2 | |
| SCHEMBL29133995 | 0.90 | ALDH1A1 (0.51) | ALDH1A1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7628975-B2 | kits for discriminating between COX-1 and COX-2 activity; screening for a tumor, monitoring anticancer treatment or antiinflammatory treatment; less invasive; 2-arachidonylglycerol is a substrate of the COX-2 enzyme, but not COX-1 | VANDERBILT UNIVERSITY (US) | 2009-12-08 | — | — | US | disclosed |
| EP-1307585-B1 | COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING COX-2 ACTIVITY AND 2-ARACHIDONYLGLYCEROL METABOLITES | UNIV VANDERBILT (US) | 2009-01-21 | — | — | EP | disclosed |
| US-7189504-B2 | Compositions and methods for detecting and quantifying COX-2 activity and 2-arachidonylglycerol metabolites | VANDERBILT UNIVERSITY (US) | 2007-03-13 | — | — | US | disclosed |
| US-20060110786-A1 | Compositions and methods for detecting and quantifying COX-2 activity and 2-arachidonylgycerol metabolites | VANDERBILT UNIVERSITY | 2006-05-25 | — | — | US | disclosed |
| EP-1307585-A4 | COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING COX-2 ACTIVITY AND 2-ARACHIDONYLGLYCEROL METABOLITES | UNIV VANDERBILT (US) | 2005-03-02 | — | — | EP | disclosed |
| EP-1307585-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING COX-2 ACTIVITY AND 2-ARACHIDONYLGLYCEROL METABOLITES | VANDERBILT UNIVERSITY (US) | 2003-05-07 | — | — | EP | disclosed |
| US-20020064804-A1 | Compositions and methods for detecting and quantifying COX-2 activity and 2-arachidonylglycerol metabolites | VANDERBILT UNIVERSITY | 2002-05-30 | — | — | US | disclosed |
| WO-2002012549-A1 | COMPOSITIONS AND METHODS FOR DETECTING AND QUANTIFYING COX-2 ACTIVITY AND 2-ARACHIDONYLGLYCEROL METABOLITES | VANDERBILT UNIVERSITY (US) | 2002-02-14 | — | — | WO | disclosed |