Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 15/20 | 0.77 |
| ▸ | MEN1 | O00255 | 13/20 | 0.77 |
| ▸ | MAPT | P10636 | 9/20 | 0.77 |
| ▸ | RECQL | P46063 | 4/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.77 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.77 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.77 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.77 |
| ▸ | APEX1 | P27695 | 2/20 | 0.77 |
| ▸ | BLM | P54132 | 2/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | GLA | P06280 | 1/20 | 0.77 |
| ▸ | DGKA | P23743 | 1/20 | 0.77 |
| ▸ | CRHBP | P24387 | 3/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893383 | 1.00 | KMT2A (0.77) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL14680208 | 0.87 | MAPT (1.00) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL29354790 | 0.87 | MAPT (1.00) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL6906446 | 0.83 | KMT2A (0.86) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL6906444 | 0.83 | KMT2A (0.86) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL3969214 | 0.80 | MEN1 (0.69) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL3969218 | 0.80 | MEN1 (0.69) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL6898866 | 0.79 | KMT2A (1.00) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL6898863 | 0.79 | KMT2A (1.00) | KMT2AMEN1MAPTRECQLMAPK1 | |
| SCHEMBL6786118 | 0.78 | KMT2A (0.81) | KMT2AMEN1MAPTRECQLMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137644-A1 | RHODANINE COMPOSITIONS FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | US | claimed |
| WO-2005041951-A2 | RHODANINE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2005-05-12 | — | — | WO | claimed |
| US-7566732-B2 | Rhodanine compositions for use as antiviral agents | RIGEL PHARMACEUTICALS, INC. (US) | 2009-07-28 | — | — | US | disclosed |
| US-20090137644-A1 | RHODANINE COMPOSITIONS FOR USE AS ANTIVIRAL AGENTS | RIGEL PHARMACEUTICALS, INC. (US) | 2009-05-28 | — | — | US | disclosed |
| US-20060276520-A1 | Rhodanine derivatives and pharmaceutical compositions containing them | RIGEL PHARMACEUTICALS, INC. (US) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276520-A1 | Rhodanine derivatives and pharmaceutical compositions containing them | UBQLN1, UBQLN2, UBE2G2 | KMT2A 901/4885MEN1 1562/4885MAPT 1187/4885 |
| US-20090137644-A1 | RHODANINE COMPOSITIONS FOR USE AS ANTIVIRAL AGENTS | RBX1, ITCH, UBQLN1 | KMT2A 1020/4885MEN1 2869/4885MAPT 880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.