ITCH
E3 ubiquitin-protein ligase Itchy homolog · Q96J02 · ITCH on Sugi Atlas →
0 patent compounds predicted against ITCH, 0 high-confidence (nearest known ligand ≥ 0.5)
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to ITCH by text similarity (a relevance ranking, not an exhaustive list)
Related proteins — ESM-2 sequence neighbours (a ITCH binder may also engage these)
| Protein | Name | Similarity | |
|---|---|---|---|
| Q8C863 | — | 1.000 | Q8C863 → |
| Q9DBH0 | — | 1.000 | Q9DBH0 → |
| Q9H0M0 | — | 0.999 | Q9H0M0 → |
| Q96PU5 | — | 0.999 | Q96PU5 → |
| Q9Y0H4 | — | 0.998 | Q9Y0H4 → |
| Q5RBF2 | — | 0.998 | Q5RBF2 → |
| Q62940 | — | 0.998 | Q62940 → |
| Q8CFI0 | — | 0.997 | Q8CFI0 → |
| SMURF2 | E3 ubiquitin-protein ligase SMURF2 | 0.997 | landscape → |
| O00308 | — | 0.997 | O00308 → |
| SMURF1 | E3 ubiquitin-protein ligase SMURF1 | 0.997 | landscape → |
| Q9N2Z7 | — | 0.996 | Q9N2Z7 → |
| Q8BZZ3 | — | 0.995 | Q8BZZ3 → |
| P46935 | — | 0.995 | P46935 → |
| Q2UBP1 | — | 0.995 | Q2UBP1 → |
| A9JRZ0 | — | 0.994 | A9JRZ0 → |
| Q9PUN2 | — | 0.994 | Q9PUN2 → |
| Q2TAS2 | — | 0.993 | Q2TAS2 → |
| Q9CUN6 | — | 0.993 | Q9CUN6 → |
| B8N7E5 | — | 0.993 | B8N7E5 → |
| P39940 | — | 0.992 | P39940 → |
| Q9VVI3 | — | 0.992 | Q9VVI3 → |
| Q92462 | — | 0.992 | Q92462 → |
| A2A5Z6 | — | 0.991 | A2A5Z6 → |
| Q9H1H9 | — | 0.991 | Q9H1H9 → |
| A1D3C5 | — | 0.991 | A1D3C5 → |
| Q757T0 | — | 0.990 | Q757T0 → |
| P25799 | — | 0.990 | P25799 → |
| Q0CCL1 | — | 0.990 | Q0CCL1 → |
| Q9UTG2 | — | 0.990 | Q9UTG2 → |