Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 18/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22363059 | 1.00 | CTSK (0.60) | CTSKCA1CA2CA7APLNR | |
| SCHEMBL26984889 | 1.00 | CTSK (0.60) | CTSKCA1CA2CA7APLNR | |
| SCHEMBL1781832 | 0.85 | CTSK (0.62) | CTSKCA1CA2CA7 | |
| SCHEMBL9644705 | 0.85 | CTSK (0.62) | CTSKCA1CA2CA7 | |
| SCHEMBL739719 | 0.85 | CTSK (0.62) | CTSKCA1CA2CA7 | |
| SCHEMBL13263255 | 0.83 | CTSK (0.60) | CTSKCA1CA2CA7 | |
| SCHEMBL29957942 | 0.82 | CTSK (0.59) | CTSKCA1CA2CA7 | |
| SCHEMBL22433834 | 0.81 | CTSK (0.63) | CTSKCA1CA2CA7 | |
| SCHEMBL374867 | 0.81 | CTSK (0.66) | CTSKCA1CA2CA7 | |
| SCHEMBL3212396 | 0.81 | CTSK (0.66) | CTSKCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084137-B1 | PEPTIDE INHIBITORS OF HEPATITIS C VIRUS NS3 PROTEASE | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-02-18 | — | — | EP | disclosed |
| US-6867284-B1 | Peptide inhibitors of hepatitis C virus NS3 protease | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2005-03-15 | — | — | US | disclosed |