Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.43 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 6/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895094 | 0.89 | CTSL (0.44) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3897625 | 0.89 | CTSL (0.44) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3897278 | 0.87 | CTSL (0.44) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3905631 | 0.85 | CTSL (0.46) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3908087 | 0.85 | CTSL (0.46) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3898431 | 0.85 | CTSL (0.50) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3897298 | 0.84 | CTSL (0.58) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3902977 | 0.84 | CTSL (0.41) | CTSLCTSSCTSKCTSB | |
| SCHEMBL3897632 | 0.84 | CTSL (0.41) | CTSLCTSSCTSKCTSB | |
| SCHEMBL7482961 | 0.84 | CTSL (0.49) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399431-B1 | NOVEL NITRILES USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2009-02-18 | — | — | EP | claimed |