Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.83 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.76 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.59 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.59 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896565 | 1.00 | FAAH (0.83) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL3896218 | 0.94 | FAAH (0.74) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL3896219 | 0.94 | FAAH (0.74) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL17309376 | 0.91 | FAAH (1.00) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL19481508 | 0.91 | FAAH (1.00) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL31310305 | 0.90 | FAAH (0.70) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL12013735 | 0.88 | FAAH (0.81) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL19481527 | 0.87 | MAPT (0.80) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL17302141 | 0.85 | FAAH (0.84) | FAAHS1PR1S1PR3MEN1KMT2A | |
| SCHEMBL11319299 | 0.85 | FAAH (0.84) | FAAHS1PR1S1PR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252940-B2 | 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection | UNIVERSITY OF WASHINGTON (US) | 2012-08-28 | — | — | US | disclosed |
| WO-2009137133-A2 | 5-SUBSTITUTED-2-IMINO-THIAZOLIDINONE COMPOUNDS AND THEIR USE AS INHIBITORS OF BACTERIAL INFECTION | UNIVERSITY OF WASHINGTON (US) | 2009-11-12 | — | — | WO | disclosed |