Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171997 | 0.84 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL11674578 | 0.83 | HPGD (0.49) | ALDH1A1SMN1; SMN2HTTMAPTMEN1 | |
| SCHEMBL1013116 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL12757681 | 0.78 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL6267441 | 0.78 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL8656250 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTMAPTMEN1 | |
| SCHEMBL11921059 | 0.78 | HPGD (0.47) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL1011078 | 0.78 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL18133119 | 0.77 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2HTTLMNAMAPT | |
| SCHEMBL10021267 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7557248-B2 | Method of forming a carbon-heteroatom bond | RHODIA CHIMIE (FR) | 2009-07-07 | — | — | US | claimed |
| US-20070243999-A1 | Method of Forming a Carbon-Heteroatom Bond | RHODIA CHIMIE (FR) | 2007-10-18 | — | — | US | claimed |
| CN-118880357-A | Benzoxazine derivative and electrochemical synthesis method thereof | 齐齐哈尔医学院 | 2024-11-01 | — | — | CN | disclosed |
| EP-1581467-B1 | LIGANDS FOR METALS AND IMPROVED METAL-CATALYZED PROCESSES BASED THEREON | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-10-12 | — | — | EP | disclosed |
| US-7557248-B2 | Method of forming a carbon-heteroatom bond | RHODIA CHIMIE (FR) | 2009-07-07 | — | — | US | disclosed |
| US-20070243999-A1 | Method of Forming a Carbon-Heteroatom Bond | RHODIA CHIMIE (FR) | 2007-10-18 | — | — | US | disclosed |