SCHEMBL389804

SCHEMBL389804

CCCCCC(C(=O)O)P(=O)(O)O

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FDPS P14324 5/20 0.57
FOLH1 Q04609 1/20 0.55
LAP3 P28838 2/20 0.53
GPR84 Q9NQS5 3/20 0.50
FFAR1 O14842 1/20 0.50
MAPT P10636 1/20 0.48
LCK P06239 1/20 0.48
PPARD Q03181 1/20 0.48
ZDHHC20 Q5W0Z9 1/20 0.48
ZDHHC2 Q9UIJ5 1/20 0.48
S1PR2 O95136 5/20 0.47
S1PR1 P21453 5/20 0.47
S1PR3 Q99500 5/20 0.47
S1PR4 O95977 4/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2339158 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
SCHEMBL3470937 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
SCHEMBL3472188 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
SCHEMBL30595172 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
SCHEMBL5575815 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
SCHEMBL9487038 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
SCHEMBL3377184 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
SCHEMBL9841018 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
SCHEMBL2023917 0.98 FDPS (0.59) FDPSFOLH1LAP3GPR84FFAR1
Butane SCHEMBL2906335 0.96 FDPS (0.57) FDPSFOLH1LAP3GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544345-B1 Corrosion and/or scale inhibition FMC CORP UK LTD (GB) 1996-08-14 EP claimed
US-5294371-A Hydroxyphosphonoacetic acid derivatives FMC CORPORATION (US) 1994-03-15 US claimed
EP-0544345-A1 Corrosion and/or scale inhibition FMC CORPORATION (UK) LIMITED (GB) 1993-06-02 EP claimed
US-20200163916-A1 PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) 2020-05-28 US disclosed
EP-3651758-A1 PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS Paris Sciences et Lettres - Quartier Latin (FR) 2020-05-20 EP disclosed
WO-2019012109-A1 PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS PARIS SCIENCES ET LETTRES - QUARTIER LATIN (FR) 2019-01-17 WO disclosed
WO-2017184428-A1 CORROSION INHIBITING FORMULATION FOR DRILLING FLUID BRINES Lubrizol Oilfield Solutions, Inc. (US) 2017-10-26 WO disclosed
US-8101635-B2 Use of glutamate antagonists which is a NMDA receptor antagonist ( ifenprodil, memantine) to reduce or control retinal pigment epithelium and/or glial migration and the subsequent development of proliferative vitreoretinopathy ( vision defect ) ALLERGAN, INC. (US) 2012-01-24 US disclosed
US-7264951-B1 Enhanced production of taxol and taxanes by cell cultures of Taxus species PHYTON, INC. (US) 2007-09-04 US disclosed
US-7230032-B2 Calcium blockers to treat proliferative vitreoretinopathy ALLERGAN, INC. (US) 2007-06-12 US disclosed
EP-0994709-A4 CALCIUM BLOCKERS TO TREAT PROLIFERATIVE VITREORETINOPATHY ALLERGAN INC (US) 2006-02-01 EP disclosed
EP-0786018-A1 CORROSION INHIBITING COMPOSITIONS FMC Corporation (UK) Limited (GB) 1997-07-30 EP disclosed
EP-0544345-B1 Corrosion and/or scale inhibition FMC CORP UK LTD (GB) 1996-08-14 EP disclosed
WO-1996011291-A1 CORROSION INHIBITING COMPOSITIONS FMC CORPORATION (UK) LIMITED (GB) 1996-04-18 WO disclosed
US-5294371-A Hydroxyphosphonoacetic acid derivatives FMC CORPORATION (US) 1994-03-15 US disclosed
EP-0544345-A1 Corrosion and/or scale inhibition FMC CORPORATION (UK) LIMITED (GB) 1993-06-02 EP disclosed
EP-0242709-A2 Antagonists of specific excitatory amino acid neurotransmitter receptors NOVA PHARMACEUTICAL CORPORATION (US) 1987-10-28 EP disclosed
WO-1987006131-A1 ANTAGONISTS OF SPECIFIC EXCITATORY AMINO ACID NEUROTRANSMITTER RECEPTORS RZESZOTARSKI JANUSZ WACLAW (US) 1987-10-22 WO disclosed
US-4657899-A ANALGESICS, COGNITION ACTIVATORS NOVA PHARMACEUTICAL CORPORATION (US) 1987-04-14 US disclosed
US-4483853-A ANTICONVULSANTS COLLINS JAMES F 1984-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200163916-A1 PROBENECID FOR USE IN TREATING EPILEPTIC DISEASES, DISORDERS OR CONDITIONS NLN, CLN6, SLC1A2 FDPS 1875/4885FOLH1 757/4885LAP3 992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.