Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665750 | 0.84 | GPR3 (0.46) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL3890065 | 0.84 | GPR3 (0.46) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL29940205 | 0.84 | GPR3 (0.46) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL28342656 | 0.76 | CA1 (0.42) | ALDH1A1HSD17B10KDM4EHPGDHTT | |
| SCHEMBL30118254 | 0.76 | NPY5R (0.37) | ALDH1A1HSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL30118271 | 0.75 | KDM4E (0.47) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL17741709 | 0.74 | CLK1 (0.42) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL30118224 | 0.73 | MEN1 (0.39) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL24871446 | 0.73 | KDM4E (0.38) | ALDH1A1HSD17B10KDM4EMAPTHPGD | |
| SCHEMBL17736562 | 0.73 | CLK1 (0.41) | ALDH1A1HSD17B10KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009027838-A2 | KINAMYCIN F FOR CANCER TREATMENT | UNIVERSITY OF MANITOBA (US) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009019616-A2 | ISOPREKINAMYCIN ANALOGS AND SYNTHESES THEREOF | UNIVERSITY OF MANITOBA (US) | 2009-02-12 | — | — | WO | disclosed |