⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL72471 | 0.86 | LMNA (0.62) | — | |
| SCHEMBL2541854 | 0.85 | LMNA (0.63) | — | |
| SCHEMBL19818557 | 0.85 | LMNA (0.52) | — | |
| SCHEMBL31402602 | 0.83 | LMNA (0.60) | — | |
| SCHEMBL6739189 | 0.83 | LMNA (0.67) | — | |
| SCHEMBL21811503 | 0.82 | — | — | |
| SCHEMBL97398 | 0.81 | LMNA (0.70) | — | |
| SCHEMBL18619 | 0.81 | LMNA (0.71) | — | |
| SCHEMBL8104259 | 0.81 | LMNA (0.78) | — | |
| SCHEMBL15391 | 0.81 | LMNA (0.78) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521396-B2 | Substituted (thioxo)carbonylaminophenyluracils | BAYER CROPSCIENCE AG (DE) | 2009-04-21 | — | — | US | claimed |
| US-20060089262-A1 | Substituted (thioxo)carbonylamino phenyl uraciles | BAYER CROPSCIENCE AG (DE) | 2006-04-27 | — | — | US | claimed |
| US-6992044-B1 | Substituted phenyluracils | BAYER CROPSCIENCE AG (DE) | 2006-01-31 | — | — | US | claimed |
| US-20040023805-A1 | Substituted phenyluracils | ANDREE ROLAND (DE) | 2004-02-05 | — | — | US | claimed |
| US-6649760-B2 | Herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-18 | — | — | US | claimed |
| EP-1272478-A1 | SUBSTITUTED PHENYLURACILS | Bayer Aktiengesellschaft (DE) | 2003-01-08 | — | — | EP | claimed |
| WO-2001077084-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2001-10-18 | — | — | WO | claimed |
| CN-106458904-B | N-substituted sulfonamide compound and process for producing the same | 宇部兴产株式会社 | 2021-12-03 | — | — | CN | disclosed |
| EP-3156396-B1 | METHOD FOR PRODUCING A N-SUBSTITUTED SULFONAMIDE COMPOUND | UBE INDUSTRIES (JP) | 2021-07-21 | — | — | EP | disclosed |
| CN-106458903-B | Method for producing heteroaromatic sulfonamide compound | 宇部兴产株式会社 | 2021-02-05 | — | — | CN | disclosed |
| US-10774072-B2 | Crystal of N-substituted sulfonamide compound | UBE INDUSTRIES, LTD. (JP) | 2020-09-15 | — | — | US | disclosed |
| US-10428046-B2 | N-substituted sulfonamide compound and method for producing same | UBE INDUSTRIES, LTD. (JP) | 2019-10-01 | — | — | US | disclosed |
| EP-3156395-B1 | METHOD FOR PRODUCING HETEROAROMATIC SULFONAMIDE COMPOUND | UBE INDUSTRIES (JP) | 2019-01-09 | — | — | EP | disclosed |
| US-5232946-A | Promoting weight gain and reduction of blood sugar and fat deposits in animals, feed efficiency | DR. KARL THOMAE GMBH (DE) | 1993-08-03 | — | — | US | disclosed |
| US-5219852-A | Hypoglycemic agents, treatment of diabetes and obesity | DR. KARL THOMAE GMBH (DE) | 1993-06-15 | — | — | US | disclosed |
| EP-0239815-B1 | SUBSTITUTED THIAZOLES AND OXAZOLES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1991-07-24 | — | — | EP | disclosed |
| US-5026702-A | Enhances physical performance in animals, effective in lowering blood sugar, reducing body fat and lowering atherogenic lipoproteins | DR. KARL THOMAE, GMBH (DE) | 1991-06-25 | — | — | US | disclosed |
| US-4886814-A | LOWER BLOOD SUGAR | DR. KARL THOMAS GMBH (DE) | 1989-12-12 | — | — | US | disclosed |
| EP-0334146-A1 | Morpholines and morpholine-N-oxides, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| EP-0239815-A1 | Substituted thiazoles and oxazoles, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-10-07 | — | — | EP | disclosed |