Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.54 |
| ▸ | PLG | P00747 | 2/20 | 0.54 |
| ▸ | PROC | P04070 | 1/20 | 0.54 |
| ▸ | KLK1 | P06870 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | LOX | P28300 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3909918 | 0.94 | F10 (0.67) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL14132012 | 0.94 | F10 (0.76) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3900630 | 0.92 | F10 (0.76) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3905955 | 0.89 | F10 (0.67) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3902464 | 0.88 | F10 (0.76) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL14132267 | 0.88 | F10 (0.76) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3895029 | 0.88 | F10 (0.86) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3900390 | 0.88 | F10 (0.66) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3911547 | 0.87 | F10 (0.77) | F10PRSS1PLGPROCKLK1 | |
| SCHEMBL14131765 | 0.87 | F10 (0.84) | F10PRSS1PLGPROCKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |