SCHEMBL3899290

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2749154	0.85	ERBB2 (0.58)	ERBB2EGFRLCKKCNH2ERBB4
	SCHEMBL3509411	0.85	EGFR (0.64)	ERBB2EGFRLCKERBB4ERBB3
	SCHEMBL27684248	0.84	ERBB2 (0.56)	ERBB2EGFRLCKKCNH2ERBB4
	SCHEMBL3507874	0.83	ERBB2 (0.53)	ERBB2EGFRKCNH2ERBB4ERBB3
	SCHEMBL2749966	0.82	ERBB2 (0.59)	ERBB2EGFRLCKKCNH2ERBB4
	SCHEMBL3506312	0.82	EGFR (0.68)	ERBB2EGFRLCKERBB4ERBB3
	Hydrochloric Acid SCHEMBL2747544	0.82	ERBB2 (0.59)	ERBB2EGFRLCKKCNH2ERBB4
	SCHEMBL2749495	0.81	EGFR (0.69)	ERBB2EGFRLCKERBB4ERBB3
	SCHEMBL2748644	0.81	EGFR (0.72)	ERBB2EGFRLCKERBB4ERBB3
	SCHEMBL27684223	0.81	ERBB2 (0.62)	ERBB2EGFRLCKKCNH2ERBB4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.