Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ATIC | P31939 | 1/20 | 0.47 |
| ▸ | HRAS | P01112 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895495 | 0.87 | MEN1 (0.55) | MEN1HTTKMT2ANPSR1HRAS | |
| SCHEMBL14132042 | 0.84 | F10 (0.61) | MEN1HTTKMT2AHRASKRAS | |
| SCHEMBL3900659 | 0.84 | MEN1 (0.52) | MEN1HTTKMT2ANPSR1HRAS | |
| SCHEMBL3910408 | 0.82 | F10 (0.63) | VNN1PARP10ALDH1A1PLGGAA | |
| SCHEMBL3897403 | 0.81 | HRAS (0.57) | MEN1HTTKMT2ANPSR1HRAS | |
| Trifluoroacetic Acid SCHEMBL3910393 | 0.79 | F2 (0.55) | F2 | |
| SCHEMBL3898931 | 0.78 | F10 (0.65) | MEN1HTTKMT2AHRASKRAS | |
| SCHEMBL3903098 | 0.78 | KAT6A (0.55) | MEN1HTTKMT2ANPSR1HRAS | |
| SCHEMBL13918681 | 0.78 | KMT2A (0.58) | MEN1HTTKMT2ANPSR1HRAS | |
| Trifluoroacetic Acid SCHEMBL3899650 | 0.74 | F10 (0.59) | F2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |