Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.55 |
| ▸ | HRAS | P01112 | 1/20 | 0.53 |
| ▸ | KRAS | P01116 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897403 | 0.97 | HRAS (0.57) | KAT6AHRASKRASALDH1A1F2 | |
| SCHEMBL3895495 | 0.84 | MEN1 (0.55) | HRASKRASALDH1A1NPSR1TDP1 | |
| SCHEMBL14712382 | 0.83 | NPSR1 (0.67) | HRASKRASALDH1A1TPSAB1NPSR1 | |
| SCHEMBL3900659 | 0.81 | MEN1 (0.52) | HRASKRASALDH1A1NPSR1TDP1 | |
| SCHEMBL14132052 | 0.80 | F2 (0.57) | KAT6AHRASKRASALDH1A1F2 | |
| SCHEMBL3899332 | 0.78 | MEN1 (0.48) | KAT6AHRASKRASALDH1A1F2 | |
| SCHEMBL14132207 | 0.76 | F2 (0.58) | KAT6AHRASKRASF2NPSR1 | |
| Trifluoroacetic Acid SCHEMBL3898961 | 0.74 | F2 (0.66) | KAT6AALDH1A1F2 | |
| SCHEMBL7972622 | 0.74 | CYP19A1 (0.56) | CYP19A1 | |
| SCHEMBL6261074 | 0.73 | ALDH1A1 (0.62) | HRASKRASALDH1A1TPSAB1NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |
| CN-1243505-A | Benzamidine derivatives | AJINOMOTO KK (JP) | 2000-02-02 | — | — | CN | disclosed |