Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342079 | 0.74 | KDM4E (0.44) | KDM4E | |
| SCHEMBL15455303 | 0.72 | SLC7A5 (0.34) | SLC7A5 | |
| SCHEMBL23139448 | 0.72 | KDM4E (0.36) | KDM4ESLC1A3SLC1A2SLC1A1 | |
| SCHEMBL23139445 | 0.72 | KDM4E (0.36) | KDM4ESLC1A3SLC1A2SLC1A1 | |
| SCHEMBL907621 | 0.71 | KDM4E (0.44) | KDM4E | |
| SCHEMBL8881280 | 0.70 | KDM4E (0.40) | KDM4E | |
| SCHEMBL26973365 | 0.70 | KDM4E (0.37) | KDM4E | |
| SCHEMBL9672400 | 0.69 | KDM4E (0.45) | KDM4E | |
| SCHEMBL19926183 | 0.68 | KDM4E (0.41) | KDM4E | |
| SCHEMBL3842916 | 0.68 | KDM4E (0.34) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090022689-A1 | C4-SPIRO-PYRROLIDINE ANTIVIRALS | ENANTA PHARMACEUTICALS, INC. | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022689-A1 | C4-SPIRO-PYRROLIDINE ANTIVIRALS | ZC3HAV1, HAVCR2, HCCS | KDM4E 1033/4885SLC7A5 1617/4885SLC1A3 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.