Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960491 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TSHR | |
| SCHEMBL2522189 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1TSHRPARP1 | |
| SCHEMBL3160945 | 0.71 | KDM4E (0.35) | KDM4EALDH1A1TSHR | |
| SCHEMBL907621 | 0.69 | KDM4E (0.44) | KDM4EALDH1A1TSHR | |
| SCHEMBL11879755 | 0.68 | ALDH1A1 (0.35) | KDM4EALDH1A1TSHR | |
| SCHEMBL27530317 | 0.68 | KDM4E (0.35) | KDM4EALDH1A1TSHR | |
| SCHEMBL3899356 | 0.68 | KDM4E (0.36) | KDM4E | |
| SCHEMBL19267416 | 0.68 | — | — | |
| SCHEMBL2926049 | 0.68 | — | — | |
| SCHEMBL2076528 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099754-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008073929-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |