Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3908371 | 1.00 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL3898079 | 0.94 | KCNA3 (0.88) | KCNA3 | |
| SCHEMBL3908635 | 0.92 | KCNA3 (0.85) | KCNA3 | |
| SCHEMBL3901643 | 0.91 | KCNA3 (0.84) | KCNA3 | |
| SCHEMBL3903211 | 0.91 | KCNA3 (0.83) | KCNA3 | |
| SCHEMBL3901594 | 0.90 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL3968487 | 0.90 | KCNA3 (0.82) | KCNA3 | |
| SCHEMBL7569017 | 0.90 | KCNA3 (0.82) | KCNA3 | |
| SCHEMBL3895291 | 0.88 | KCNA3 (0.87) | KCNA3 | |
| SCHEMBL3895286 | 0.88 | KCNA3 (0.87) | KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143965-B1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2009-02-25 | — | — | EP | claimed |
| EP-1368020-B1 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO INC (US) | 2008-03-05 | — | — | EP | claimed |
| US-20040115739-A1 | Method for identifying maxi-k channel blockers for use in lowering elevated intraocular pressure using hek-293 cells | GARCIA MARIA L (US) | 2004-06-17 | — | — | US | claimed |
| EP-1368020-A4 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO INC (US) | 2004-05-12 | — | — | EP | claimed |
| EP-1368020-A2 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | Merck & Co., Inc. (US) | 2003-12-10 | — | — | EP | claimed |
| US-6632836-B1 | To treat autoimmune disorders, cardiac arrhythmias and the like | MERCK & CO., INC. | 2003-10-14 | — | — | US | claimed |
| WO-2002060340-A9 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO INC (US) | 2002-11-21 | — | — | WO | claimed |
| EP-1143965-A4 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2002-10-09 | — | — | EP | claimed |
| WO-2002060340-A2 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2002-08-08 | — | — | WO | claimed |
| EP-1143965-A1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2001-10-17 | — | — | EP | claimed |
| WO-2000025770-A1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | claimed |
| EP-1143965-B1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2009-02-25 | — | — | EP | disclosed |
| EP-1368020-B1 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO INC (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20040115739-A1 | Method for identifying maxi-k channel blockers for use in lowering elevated intraocular pressure using hek-293 cells | GARCIA MARIA L (US) | 2004-06-17 | — | — | US | disclosed |
| EP-1368020-A4 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO INC (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2002060340-A9 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO INC (US) | 2002-11-21 | — | — | WO | disclosed |
| EP-1143965-A4 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2002060340-A2 | METHOD FOR IDENTIFYING MAXI-K CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2002-08-08 | — | — | WO | disclosed |
| EP-1143965-A1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000025770-A1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |