Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 19/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3968487 | 1.00 | KCNA3 (0.82) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3899524 | 0.90 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL3908371 | 0.90 | KCNA3 (1.00) | KCNA3 | |
| SCHEMBL3898206 | 0.86 | MEN1 (0.70) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3898203 | 0.86 | MEN1 (0.70) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3898201 | 0.86 | MEN1 (0.70) | KCNA3MEN1ALDH1A1KMT2A | |
| SCHEMBL3898079 | 0.84 | KCNA3 (0.88) | KCNA3 | |
| SCHEMBL3908635 | 0.83 | KCNA3 (0.85) | KCNA3 | |
| SCHEMBL3901643 | 0.82 | KCNA3 (0.84) | KCNA3 | |
| SCHEMBL3901594 | 0.81 | KCNA3 (1.00) | KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143965-A4 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2002-10-09 | — | — | EP | disclosed |
| EP-1143965-A1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | Merck & Co., Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000025770-A1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO., INC. (US) | 2000-05-11 | — | — | WO | disclosed |