Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585795 | 1.00 | ELANE (0.51) | ELANEKMT2AATMMAPTRAB9A | |
| SCHEMBL30971 | 0.95 | ELANE (0.56) | ELANEKMT2AATMMAPTRAB9A | |
| SCHEMBL14173071 | 0.95 | ELANE (0.56) | ELANEKMT2AATMMAPTRAB9A | |
| Methacrylic Acid SCHEMBL8101356 | 0.90 | ELANE (0.55) | ELANEKMT2AATMMAPTRAB9A | |
| SCHEMBL25926581 | 0.90 | ELANE (0.51) | ELANEKMT2AATMMAPTRAB9A | |
| SCHEMBL51951 | 0.89 | ESR1 (0.52) | ELANEKMT2AATMMAPTHPGD | |
| SCHEMBL19320624 | 0.89 | ELANE (0.50) | ELANEKMT2AATMMAPTRAB9A | |
| SCHEMBL36873 | 0.89 | ELANE (0.62) | ELANEKMT2AATMMAPTRAB9A | |
| SCHEMBL27822727 | 0.89 | ELANE (0.50) | ELANEKMT2AATMMAPTRAB9A | |
| SCHEMBL12277346 | 0.88 | ELANE (0.58) | ELANEKMT2AATMMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1741419-B1 | Dental material with unusual fluorine distribution | IVOCLAR VIVADENT AG (LI) | 2009-02-25 | — | — | EP | claimed |