Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14173071 | 0.95 | ELANE (0.56) | ELANEKMT2AATMTDP1MAPT | |
| SCHEMBL30971 | 0.95 | ELANE (0.56) | ELANEKMT2AATMTDP1MAPT | |
| SCHEMBL36873 | 0.92 | ELANE (0.62) | ELANEKMT2AATMTDP1MAPT | |
| 1,6-Hexanediol SCHEMBL6668642 | 0.90 | ELANE (0.47) | ELANEKMT2AATMTDP1MAPT | |
| SCHEMBL25926581 | 0.90 | ELANE (0.51) | ELANEKMT2AATMTDP1MAPT | |
| SCHEMBL8585795 | 0.90 | ELANE (0.51) | ELANEKMT2AATMTDP1MAPT | |
| SCHEMBL3899570 | 0.90 | ELANE (0.51) | ELANEKMT2AATMTDP1MAPT | |
| SCHEMBL19320624 | 0.89 | ELANE (0.50) | ELANEKMT2AATMTDP1MAPT | |
| SCHEMBL27822727 | 0.89 | ELANE (0.50) | ELANEKMT2AATMTDP1MAPT | |
| SCHEMBL51951 | 0.89 | ESR1 (0.52) | ELANEKMT2AATMTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136886-A | RUBBER | KABUSHIKI KAISHA SHOFU (JP) | 2000-10-24 | — | — | US | disclosed |
| US-6063830-A | SILICA AND URETHANEACRYLATE | KABUSHIKI KAISHA SHOFU (JP) | 2000-05-16 | — | — | US | disclosed |