Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.56 |
| ▸ | PLG | P00747 | 2/20 | 0.56 |
| ▸ | PROC | P04070 | 1/20 | 0.56 |
| ▸ | KLK1 | P06870 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | C1S | P09871 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13901202 | 0.95 | F10 (0.71) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3900623 | 0.86 | F10 (0.79) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3895029 | 0.86 | F10 (0.86) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3903060 | 0.84 | F10 (0.79) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3911481 | 0.83 | F10 (0.81) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3911547 | 0.83 | F10 (0.77) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3903054 | 0.83 | F10 (0.77) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3900211 | 0.83 | F10 (0.80) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3912344 | 0.83 | F10 (0.80) | F10PRSS1PLGPROCKLK1 | |
| Trifluoroacetic Acid SCHEMBL3898866 | 0.83 | F10 (0.62) | F10PRSS1PLGPROCKLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |