Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30602832 | 0.91 | POLB (0.36) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL554511 | 0.91 | POLB (0.36) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL21641727 | 0.86 | RXFP1 (0.32) | MAPT | |
| SCHEMBL9467307 | 0.82 | KDM4E (0.34) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL18280470 | 0.82 | KDM4E (0.35) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL21586947 | 0.82 | PDE2A (0.36) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL21586951 | 0.82 | PDE2A (0.35) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL30887157 | 0.82 | PDE2A (0.36) | MAPTALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL25282759 | 0.82 | POLB (0.32) | MAPT | |
| SCHEMBL9467298 | 0.82 | CYP1A2 (0.34) | MAPTLMNASMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664855-B1 | PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS | BAUSCH & LOMB (US) | 2009-03-11 | — | — | EP | claimed |