Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417192 | 0.90 | NPC1 (0.36) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL30602832 | 0.89 | POLB (0.36) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL554511 | 0.89 | POLB (0.36) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL18280470 | 0.88 | KDM4E (0.35) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL21586951 | 0.84 | PDE2A (0.35) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL21586947 | 0.84 | PDE2A (0.36) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL30887157 | 0.84 | PDE2A (0.36) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL3899772 | 0.82 | MAPT (0.33) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL9417231 | 0.82 | NPC1 (0.35) | KDM4EALDH1A1LMNASMN1; SMN2NPSR1 | |
| SCHEMBL23636577 | 0.81 | MTNR1A (0.38) | KDM4EALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250359-A | Weather resistant, abrasion resistant undercoatings | NIPPON ARC CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5191045-A | Protective coatings with radiation resistance for moldings | NIPPON ARC CO., LTD. (JP) | 1993-03-02 | — | — | US | disclosed |