Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 10/20 | 0.83 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3902772 | 0.95 | F10 (0.74) | F10F2F7F3 | |
| SCHEMBL3899344 | 0.91 | F10 (1.00) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL3898935 | 0.91 | F10 (1.00) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14131785 | 0.90 | F10 (0.83) | F10PLAUPRSS1F2PLG | |
| SCHEMBL13901150 | 0.90 | F10 (0.83) | F10PLAUPRSS1F2PLG | |
| SCHEMBL14131786 | 0.89 | F10 (0.92) | F10PLAUPRSS1F2PLG | |
| SCHEMBL14132009 | 0.89 | F10 (0.65) | F10PLAUALDH1A1RAB9APRSS1 | |
| SCHEMBL14132008 | 0.87 | F10 (0.88) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL3907519 | 0.86 | F10 (0.61) | F10PLAUALDH1A1RAB9AHPGD | |
| Trifluoroacetic Acid SCHEMBL3898447 | 0.85 | F10 (0.74) | F10PRSS1F2F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |