Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 6/20 | 0.39 |
| ▸ | CTSK | P43235 | 5/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PCNA | P12004 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465898 | 0.90 | ATM (0.51) | ATMPPARGPPARAITGB3ITGA2B | |
| SCHEMBL7465905 | 0.90 | ATM (0.51) | ATMPPARGPPARAITGB3ITGA2B | |
| SCHEMBL21852432 | 0.85 | ACACB (0.51) | ATMITGB3ITGA2BACACBHDAC8 | |
| SCHEMBL21852417 | 0.85 | ACACB (0.51) | ATMITGB3ITGA2BACACBHDAC8 | |
| SCHEMBL1759628 | 0.83 | ATM (0.52) | ATMPPARGPPARAAPPSYK | |
| SCHEMBL1759626 | 0.83 | ATM (0.52) | ATMPPARGPPARAAPPSYK | |
| SCHEMBL22734404 | 0.83 | ATM (0.53) | ATMITGB3ITGA2BAPPACACB | |
| SCHEMBL20661670 | 0.83 | ATM (0.53) | ATMPPARGPPARAITGB3ITGA2B | |
| SCHEMBL13919604 | 0.83 | ATM (0.53) | ATMITGB3ITGA2BAPPACACB | |
| SCHEMBL22774852 | 0.83 | ATM (0.53) | ATMITGB3ITGA2BAPPACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |