Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3900562

N=C(N)c1cccc(OCCNC(=O)c2ccc(C(=O)N3CCNCC3)cc2)c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.75
F2 P00734 1/20 0.52
PRSS1 P07477 5/20 0.51
PLG P00747 1/20 0.51
PROC P04070 1/20 0.51
KLK1 P06870 1/20 0.51
NPC1 O15118 1/20 0.44
HPGD P15428 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14132282 0.95 F10 (0.83) F10F2PRSS1PLGPROC
Trifluoroacetic Acid SCHEMBL3901365 0.92 F10 (0.89) F10F2PRSS1PLGPROC
Trifluoroacetic Acid SCHEMBL5105095 0.91 F10 (0.87) F10F2PRSS1PLGPROC
Trifluoroacetic Acid SCHEMBL3903303 0.90 F10 (0.75) F10F2PRSS1PLGPROC
Trifluoroacetic Acid SCHEMBL3899429 0.86 F10 (0.60) F10F2PRSS1PLGPROC
SCHEMBL14132262 0.86 F10 (1.00) F10F2PRSS1PLGPROC
Trifluoroacetic Acid SCHEMBL3895029 0.86 F10 (0.86) F10F2PRSS1PLGPROC
SCHEMBL14132003 0.85 F10 (0.98) F10F2PRSS1PLGPROC
Trifluoroacetic Acid SCHEMBL3903060 0.84 F10 (0.79) F10F2PRSS1PLGPROC
Trifluoroacetic Acid SCHEMBL3896028 0.83 F10 (0.68) F10F2PRSS1PLGPROC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976722-B1 BENZAMIDINE DERIVATIVES AJINOMOTO KK (JP) 2009-03-11 EP disclosed
US-7396844-B1 Benzamidine derivatives AJINOMOTO CO., INC. (JP) 2008-07-08 US disclosed
EP-0976722-A1 BENZAMIDINE DERIVATIVES Ajinomoto Co., Inc. (JP) 2000-02-02 EP disclosed