Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.59 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.59 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.53 |
| ▸ | CPT1A | P50416 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9240379 | 0.81 | CHRNB4 (0.48) | HCRTR1HCRTR2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL3912244 | 0.81 | CHRNB4 (0.48) | HCRTR1HCRTR2CHRNB4CHRNA3CHRNB2 | |
| SCHEMBL14132338 | 0.80 | SPHK2 (0.53) | HCRTR1HCRTR2SPHK2SPHK1 | |
| SCHEMBL3093335 | 0.80 | HRH3 (0.53) | HCRTR1HCRTR2DPP4HRH3 | |
| SCHEMBL3093346 | 0.80 | HRH3 (0.53) | HCRTR1HCRTR2DPP4HRH3 | |
| SCHEMBL3614551 | 0.78 | CHRNB4 (0.69) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL9244259 | 0.78 | CHRNB4 (0.69) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL4270669 | 0.77 | HCRTR1 (0.55) | HCRTR1HCRTR2SPHK2SPHK1EGLN1 | |
| SCHEMBL4270666 | 0.77 | HCRTR1 (0.55) | HCRTR1HCRTR2SPHK2SPHK1EGLN1 | |
| Hydrochloric Acid SCHEMBL9242770 | 0.77 | CHRNB4 (0.67) | CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |