Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 6/20 | 0.69 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.69 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.67 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.67 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.62 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614551 | 1.00 | CHRNB4 (0.69) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| Hydrochloric Acid SCHEMBL9242770 | 0.99 | CHRNB4 (0.67) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| Hydrochloric Acid SCHEMBL9242766 | 0.99 | CHRNB4 (0.67) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL11466424 | 0.90 | CHRNB4 (0.55) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL11466251 | 0.87 | HCRTR1 (0.56) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL3605852 | 0.84 | CHRNB4 (0.49) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL9243572 | 0.82 | CHRNB4 (0.70) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL9242858 | 0.82 | CHRNB4 (0.70) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| SCHEMBL8439489 | 0.82 | CHRNB2 (0.80) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 | |
| Hydrochloric Acid SCHEMBL9243326 | 0.81 | CHRNB4 (0.68) | CHRNB4CHRNA3CHRNB2CHRNA4CHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | claimed |
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | disclosed |