Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895042 | 0.91 | NR3C1 (0.58) | NR3C1SMO | |
| SCHEMBL3016202 | 0.85 | NR3C1 (0.63) | NR3C1SMO | |
| SCHEMBL3011848 | 0.81 | NR3C1 (0.55) | NR3C1SMO | |
| SCHEMBL3892754 | 0.79 | NR3C1 (0.54) | NR3C1SMO | |
| 2,2,2-Trifluoro-1-(4-Fluorophenyl)-1-(1-(4-Fluorophenyl)-1H-Indazol-5-Yl)Ethanol (Diastereomeric Mix) SCHEMBL4280142 | 0.78 | NR3C1 (1.00) | NR3C1 | |
| SCHEMBL2999977 | 0.78 | NR3C1 (0.57) | NR3C1SMO | |
| SCHEMBL3018350 | 0.77 | NR3C1 (0.62) | NR3C1SMO | |
| SCHEMBL3000307 | 0.77 | NR3C1 (0.59) | NR3C1SMO | |
| SCHEMBL3000515 | 0.77 | NR3C1 (0.59) | NR3C1SMO | |
| SCHEMBL3014673 | 0.77 | NR3C1 (0.59) | NR3C1SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102170-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008070507-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-12 | — | — | WO | disclosed |