Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897181 | 0.93 | F10 (0.60) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| SCHEMBL3898858 | 0.90 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| SCHEMBL3910408 | 0.89 | F10 (0.63) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| SCHEMBL3901290 | 0.89 | POLB (0.59) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| SCHEMBL3901294 | 0.89 | F10 (0.60) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| SCHEMBL3902858 | 0.89 | RAB9A (0.58) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| SCHEMBL3899288 | 0.88 | POLB (0.58) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| Hydrochloric Acid SCHEMBL3898352 | 0.87 | F10 (0.58) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| SCHEMBL3911536 | 0.86 | POLB (0.56) | NPC1RAB9ASMN1; SMN2HPGDF10 | |
| SCHEMBL3906076 | 0.86 | POLB (0.56) | NPC1RAB9ASMN1; SMN2HPGDF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |