Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGFR | P43088 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902542 | 0.94 | HSD11B1 (0.55) | HSD11B1ALOX5LMNASLC22A6TSHR | |
| SCHEMBL10761559 | 0.92 | HSD11B1 (0.53) | HSD11B1ALOX5LMNATSHRPMP22 | |
| SCHEMBL10757417 | 0.92 | HSD11B1 (0.53) | HSD11B1ALOX5LMNATSHRPMP22 | |
| SCHEMBL11030817 | 0.92 | HSD11B1 (0.53) | HSD11B1ALOX5LMNATSHRPMP22 | |
| SCHEMBL10756960 | 0.92 | HSD11B1 (0.53) | HSD11B1ALOX5LMNATSHRPMP22 | |
| SCHEMBL6159955 | 0.87 | HSD11B1 (0.61) | HSD11B1ALOX5LMNASLC22A6EPHX2 | |
| SCHEMBL2093413 | 0.83 | HSD11B1 (0.47) | HSD11B1TSHREPHX2L3MBTL1KMT2A | |
| SCHEMBL1787432 | 0.73 | HSD11B1 (1.00) | HSD11B1EPHX2L3MBTL1SLC6A12SLC6A11 | |
| SCHEMBL10759084 | 0.72 | HSD11B1 (0.44) | HSD11B1EPHX2TBXA2RPTGFRPTGER2 | |
| SCHEMBL10936787 | 0.71 | EPHX2 (0.48) | HSD11B1LMNATSHREPHX2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426545-A | Adamantyl carboxylic and sulfonic acid catalyzed paraffin-olefin alkylation | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-01-17 | — | — | US | claimed |
| EP-1646383-A4 | DESIGN AND SYNTHESIS OF OPTIMIZED LIGANDS FOR PPAR | BETHESDA PHARMACEUTICALS INC (US) | 2009-03-25 | — | — | EP | disclosed |
| US-7339065-B2 | Design and synthesis of optimized ligands for PPAR | BETHESDA PHARMACEUTICALS, INC. (US) | 2008-03-04 | — | — | US | disclosed |
| US-20070099969-A1 | Design and synthesis of optimized ligands for ppar | THE UNIVERSITY OF MISSISSIPPI | 2007-05-03 | — | — | US | disclosed |
| EP-1646383-A1 | DESIGN AND SYNTHESIS OF OPTIMIZED LIGANDS FOR PPAR | Bethesda Pharmaceuticals, Inc. (US) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005009437-A1 | DESIGN AND SYNTHESIS OF OPTIMIZED LIGANDS FOR PPAR | BETHESDA PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| EP-0119359-B1 | ADAMANTYL CARBOXYLIC AND SULFONIC ACID CATALYZED PARAFFIN-OLEFIN ALKYLATION AND PARAFFIN ISOMERIZATION | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1987-06-10 | — | — | EP | disclosed |
| EP-0119359-A1 | Adamantyl carboxylic and sulfonic acid catalyzed paraffin-olefin alkylation and paraffin isomerization | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1984-09-26 | — | — | EP | disclosed |
| US-4426545-A | Adamantyl carboxylic and sulfonic acid catalyzed paraffin-olefin alkylation | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-01-17 | — | — | US | disclosed |
| US-4424387-A | STRONG ACID, BRANCHING | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099969-A1 | Design and synthesis of optimized ligands for ppar | PPARD, PPARA, PPARG | HSD11B1 828/4885ALOX5 37/4885LMNA 2709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.