⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625648 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL9468511 | 0.72 | — | — | |
| SCHEMBL16703905 | 0.72 | — | — | |
| SCHEMBL12301381 | 0.72 | — | — | |
| SCHEMBL15264492 | 0.72 | — | — | |
| SCHEMBL13796541 | 0.72 | — | — | |
| SCHEMBL217393 | 0.72 | — | — | |
| SCHEMBL2195854 | 0.72 | — | — | |
| SCHEMBL15263884 | 0.72 | ALDH1A1 (0.43) | — | |
| SCHEMBL16715455 | 0.72 | TP53 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006065590-A2 | PYRIDINE AND PYRIMIDINE ANTIVIRAL COMPOSITIONS | XTL BIOPHARMACEUTICALS INC. (US) | 2006-06-22 | — | — | WO | claimed |
| WO-2025129168-A1 | TRIAZOLONE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |
| EP-3541804-B1 | CYCLOALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2025-01-22 | — | — | EP | disclosed |
| EP-3541802-B1 | ALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2025-01-01 | — | — | EP | disclosed |
| WO-2024054953-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |
| US-11191762-B2 | Alkyl substituted triazole compounds as agonists of the APJ Receptor | AMGEN INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-11191762-B2 | Alkyl substituted triazole compounds as agonists of the APJ Receptor | AMGEN INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-11046680-B1 | Heteroaryl-substituted triazoles as APJ receptor agonists | AMGEN INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-11046680-B1 | Heteroaryl-substituted triazoles as APJ receptor agonists | AMGEN INC. (US) | 2021-06-29 | — | — | US | disclosed |
| US-11020395-B2 | Cycloalkyl substituted triazole compounds as agonists of the APJ receptor | AMGEN INC. (US) | 2021-06-01 | — | — | US | disclosed |
| EP-1539738-B1 | NOVEL ARYL- 4-HALO-4- HETEROARYLMETHYLAMINO)-METHYL -PIPERIDIN-1-YL -METHANONE DERIVATIVES, METHODS FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | PF MEDICAMENT (FR) | 2009-03-04 | — | — | EP | disclosed |
| CN-101285094-A | Primer, primer set, and nucleic acid amplification method and mutation detection method using the same | RIKEN (JP) | 2008-10-15 | — | — | CN | disclosed |
| CN-1308325-C | Novel aryl- { 4-halogen-4- [ (heteroarylmethylamino) methyl ] -piperidin-1-yl } methanone derivatives, process for their preparation and their use as medicaments | PF MEDICAMENT (FR) | 2007-04-04 | — | — | CN | disclosed |
| US-20060100244-A1 | Novel aryl-[4-halo-4(heteroarylmethylamino)-methyl]-piperidin-1-1yl]-methanone derivatives, methods for production and use thereof as medicaments | PIERRE FABRE MEDICAMENT (FR) | 2006-05-11 | — | — | US | disclosed |
| CN-1675194-A | Novel aryl- { 4-halogen-4- [ (heteroarylmethylamino) methyl ] -piperidin-1-yl } methanone derivatives, process for their preparation and their use as medicaments | PF MEDICAMENT (FR) | 2005-09-28 | — | — | CN | disclosed |
| EP-1539738-A1 | NOVEL ARYL- 4-HALO-4- HETEROARYLMETHYLAMINO)-METHYL]-PIPERIDIN-1-YL -METHANONE DERIVATIVES, METHODS FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 2005-06-15 | — | — | EP | disclosed |
| WO-2003106449-A1 | NOVEL ARYL-{4-HALO-4-[HETEROARYLMETHYLAMINO)-METHYL]-PIPERIDIN-1-YL}-METHANONE DERIVATIVES, METHODS FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | PIERRE FABRE MEDICAMENT (FR) | 2003-12-24 | — | — | WO | disclosed |
| US-4938793-A | Herbicide, plant growth regulator | ICI AUSTRALIA LIMITED (AU) | 1990-07-03 | — | — | US | disclosed |
| US-4923989-A | Compounds and compositions | ICI AUSTRALIA LIMITED (AU) | 1990-05-08 | — | — | US | disclosed |
| EP-0102823-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-03-14 | — | — | EP | disclosed |