Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.66 |
| ▸ | F2 | P00734 | 5/20 | 0.66 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.37 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.37 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13901228 | 0.96 | F10 (0.72) | F10F2ROCK2PRSS1PRSS2 | |
| SCHEMBL14132033 | 0.83 | F10 (0.77) | F10F2PDE4APDE4BPDE4C | |
| Trifluoroacetic Acid SCHEMBL3900529 | 0.83 | F10 (0.62) | F10F2ROCK2PRSS1PRSS2 | |
| Trifluoroacetic Acid SCHEMBL3905842 | 0.81 | F10 (0.72) | F10F2ROCK2PRSS1PRSS2 | |
| SCHEMBL14132315 | 0.81 | F10 (1.00) | F10F2PRSS1PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL3899621 | 0.80 | F10 (0.75) | F10F2PRSS1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3897265 | 0.80 | F10 (0.75) | F10F2PRSS1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL3902136 | 0.80 | F10 (0.74) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL3905673 | 0.80 | F10 (0.92) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL3894473 | 0.77 | F10 (0.93) | F10F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |