⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11217194 | 0.80 | TSHR (0.31) | — | |
| SCHEMBL3901619 | 0.78 | — | — | |
| SCHEMBL1107 | 0.77 | — | — | |
| SCHEMBL1947 | 0.71 | TSHR (0.31) | — | |
| SCHEMBL5162099 | 0.70 | — | — | |
| SCHEMBL9907031 | 0.68 | — | — | |
| SCHEMBL3896758 | 0.68 | — | — | |
| Propylformate SCHEMBL30995061 | 0.68 | ALDH1A1 (0.35) | — | |
| Propylformate SCHEMBL18445 | 0.68 | — | — | |
| SCHEMBL2259342 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7585973-B2 | Process for producing folic acid derivatives | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-09-08 | — | — | US | claimed |
| US-7585973-B2 | Process for producing folic acid derivatives | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2009-09-08 | — | — | US | disclosed |
| US-20070142387-A1 | Process for producing folic acid derivatives | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-06-21 | — | — | US | disclosed |
| EP-1734044-A1 | PROCESS FOR PRODUCING FOLIC ACID DERIVATIVE | Japan Science and Technology Agency (JP) | 2006-12-20 | — | — | EP | disclosed |