Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ICMT | O60725 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25212014 | 0.88 | MRGPRX4 (0.48) | ARKDM4ETRPV4ESR1ICMT | |
| SCHEMBL7356606 | 0.84 | AR (0.46) | ARKDM4ETRPV4TSHRCYP19A1 | |
| SCHEMBL27001716 | 0.83 | AR (0.45) | ARKDM4ETRPV4TSHRCYP19A1 | |
| SCHEMBL12460421 | 0.83 | AR (0.49) | ARKDM4ETRPV4TSHRCYP19A1 | |
| SCHEMBL13904208 | 0.81 | KDM4E (0.40) | ARKDM4ETRPV4CYP19A1CYP11B1 | |
| SCHEMBL3905446 | 0.81 | KDM4E (0.40) | ARKDM4ETRPV4CYP19A1CYP11B1 | |
| SCHEMBL5418640 | 0.80 | TRPV4 (0.59) | ARTRPV4MRGPRX4PTGDR2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3896102 | 0.80 | KDM4E (0.43) | ARKDM4ETRPV4CYP19A1CYP11B1 | |
| SCHEMBL12461366 | 0.80 | MRGPRX4 (0.47) | ARTRPV4ESR1ICMTMAPT | |
| SCHEMBL25823520 | 0.78 | TSHR (0.59) | KDM4ETSHRTAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |
| CN-1243505-A | Benzamidine derivatives | AJINOMOTO KK (JP) | 2000-02-02 | — | — | CN | disclosed |