SCHEMBL390280

SCHEMBL390280

Cc1cc(C)nc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30578987 1.00
SCHEMBL19341243 1.00
SCHEMBL165100 0.85
SCHEMBL9472907 0.78 NOS3 (0.63)
SCHEMBL7489 0.78
SCHEMBL1050198 0.78 NOS3 (0.63)
SCHEMBL29434174 0.78
SCHEMBL380662 0.78
Hypochlorous Acid SCHEMBL6563538 0.77 NOS3 (0.55)
Fluoride SCHEMBL893225 0.76 NOS3 (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111548269-B Preparation method of diaryl methane structural compound 兰州大学 2023-10-27 CN claimed
CN-111548269-A Preparation method of diarylmethane structure compound 兰州大学 2020-08-18 CN claimed
US-20230399302-A1 PROCESS FOR THE PREPARATION OF HETEROARYL-SUBSTITUTED SULFUR(VI) COMPOUNDS NATIONAL INSTITUTES OF HEALTH 2023-12-14 US disclosed
CN-111548269-B Preparation method of diaryl methane structural compound 兰州大学 2023-10-27 CN disclosed
US-20230303510-A1 CYCLIZED ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. 2023-09-28 US disclosed
US-20230303510-A1 CYCLIZED ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. 2023-09-28 US disclosed
US-20230303510-A1 CYCLIZED ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. 2023-09-28 US disclosed
EP-4188918-A1 CYCLIZED ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS Ideaya Biosciences, Inc. (US) 2023-06-07 EP disclosed
WO-2023091604-A1 ADENOSINE RECEPTOR ANTAGONISTS CROSSIGNAL THERAPEUTICS, INC. (US) 2023-05-25 WO disclosed
WO-2022026565-A9 CYCLIZED ACETAMIDO DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. (US) 2022-12-08 WO disclosed
EP-3686199-B9 FUSED RING DERIVATIVE AS A2A RECEPTOR INHIBITOR CSTONE PHARMACEUTICALS SUZHOU CO LTD (CN) 2022-12-07 EP disclosed
EP-0499328-A2 Process for the preparation of diarylphosphino pyridines SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-08-19 EP disclosed
US-4898608-A Pyridylthio-acylanilide herbicides BAYER AKTIENGESELLSCHAFT (DE) 1990-02-06 US disclosed
US-4871387-A Pyri(mi)dyl-oxy-and -thio-benzoic acid derivatives useful as herbicides and plant growth regulants BAYER AKTIENGESELLSCHAFT (DE) 1989-10-03 US disclosed
EP-0273242-A2 2-Pyri(mi)dylthio-aryl ether BAYER AG (DE) 1988-07-06 EP disclosed
EP-0243868-A2 Pyridylthio-acylanilides BAYER AG (DE) 1987-11-04 EP disclosed
US-4684693-A Thermosettable polymer or prepolymer prepared from heterocyclic materials containing a nitrogen atom and carboxylic acid mono- or dianhydride with N,N'-bis-imide THE DOW CHEMICAL COMPANY (US) 1987-08-04 US disclosed
EP-0226837-A2 Pyri(mi)dyloxy and -thiobenzoic acid derivatives BAYER AG (DE) 1987-07-01 EP disclosed
US-4668767-A Thermosettable polymer or prepolymer prepared from heterocyclic material containing a nitrogen atom and carboxylic acid mono- or dianhydride THE DOW CHEMICAL COMPANY (US) 1987-05-26 US disclosed
US-4647616-A Thermosettable polymer or prepolymer prepared from herterocycle material containing a nitrogen atom and carboxylic acid mono- or dianhydride THE DOW CHEMICAL COMPANY (US) 1987-03-03 US disclosed