Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 18/20 | 0.76 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902035 | 0.93 | HSD11B1 (0.80) | HSD11B1KMO | |
| SCHEMBL350758 | 0.87 | HSD11B1 (0.67) | HSD11B1 | |
| SCHEMBL349468 | 0.87 | HSD11B1 (1.00) | HSD11B1CNR1GPR55 | |
| SCHEMBL3909514 | 0.86 | HSD11B1 (0.79) | HSD11B1CNR1GPR55 | |
| SCHEMBL348554 | 0.82 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL348767 | 0.81 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL350129 | 0.81 | HSD11B1 (0.74) | HSD11B1 | |
| SCHEMBL349025 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL349249 | 0.80 | HSD11B1 (1.00) | HSD11B1 | |
| SCHEMBL350885 | 0.79 | HSD11B1 (0.81) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756063-A4 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2009-03-25 | — | — | EP | claimed |
| EP-1756063-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2005110992-A1 | AMIDO COMPOUNDS AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2005-11-24 | — | — | WO | claimed |