Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902114 | 0.78 | TAAR1 (0.52) | LTA4HPOLBTP53TDP1GAA | |
| SCHEMBL1133289 | 0.77 | MGAM (0.47) | LTA4HPOLBTDP1GAAMGAM | |
| SCHEMBL3902061 | 0.75 | S1PR4 (0.36) | TP53GAAS1PR4MAPTKDM4E | |
| SCHEMBL3904012 | 0.73 | CYP46A1 (0.36) | POLBGAAMGAMSIMGAM2 | |
| SCHEMBL5050611 | 0.71 | MYC (0.44) | DPP4ALDH1A1 | |
| SCHEMBL13042664 | 0.71 | CD44 (0.45) | POLBTDP1DPP4ALDH1A1KDM4E | |
| SCHEMBL6371894 | 0.71 | CD44 (0.45) | LTA4HPOLBTDP1GAAMGAM | |
| SCHEMBL3364100 | 0.70 | ESR1 (0.41) | TP53GAAMAPTALDH1A1GLA | |
| SCHEMBL168282 | 0.69 | TAAR1 (0.46) | POLBGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29767673 | 0.69 | TAAR1 (0.46) | POLBGAAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |